Assessment by Thallium-201 of Hindlimb Muscle Blood Flow in Rats during Recovery after Hindlimb Unloading
نویسندگان
چکیده
منابع مشابه
Rat hindlimb muscle blood flow during level and downhill locomotion.
During eccentrically biased exercise (e.g., downhill locomotion), whole body oxygen consumption and blood lactate concentrations are lower than during level locomotion. These general systemic measurements indicate that muscle metabolism is lower during downhill exercise. This study was designed to test the hypothesis that hindlimb muscle blood flow is correspondingly lower during downhill vs. l...
متن کاملDifferential bone and muscle recovery following hindlimb unloading in skeletally mature male rats.
This study was designed to track the recovery of bone and muscle properties after 28 days of hindlimb unloading (HU) in skeletally mature male rats in order to quantify the degree and timing of the expected mismatch between bone and muscle properties. Outcome variables were in vivo plantarflexor peak isometric torque and proximal tibial volumetric bone mineral density (vBMD). Proximal tibia vBM...
متن کاملMuscle regeneration during hindlimb unloading results in a reduction in muscle size after reloading.
The hindlimb-unloading model was used to study the ability of muscle injured in a weightless environment to recover after reloading. Satellite cell mitotic activity and DNA unit size were determined in injured and intact soleus muscles from hindlimb-unloaded and age-matched weight-bearing rats at the conclusion of 28 days of hindlimb unloading, 2 wk after reloading, and 9 wk after reloading. Th...
متن کاملRegulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats.
In the rat, denervation and hindlimb unloading are two commonly employed models used to study skeletal muscle atrophy. In these models, muscle atrophy is generally produced by a decrease in protein synthesis and an increase in protein degradation. The decrease in protein synthesis has been suggested to occur by an inhibition at the level of protein translation. To better characterize the regula...
متن کاملHindlimb unloading alters ligament healing.
We investigated the hypothesis that hindlimb unloading inhibits healing in fibrous connective tissue such as ligament. Male rats were assigned to 3- and 7-wk treatment groups with three subgroups each: sham control, ambulatory healing, and hindlimb-suspended healing. Ambulatory and suspended animals underwent surgical rupture of their medial collateral ligaments, whereas sham surgeries were per...
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ژورنال
عنوان ژورنال: Journal of Physical Therapy Science
سال: 2009
ISSN: 0915-5287,2187-5626
DOI: 10.1589/jpts.21.163